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CARD11 抗体 (AA 301-400)

This anti-CARD11 antibody is a 兔 多克隆 antibody detecting CARD11 in WB, ELISA, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN715691
发货至: 中国

Quick Overview for CARD11 抗体 (AA 301-400) (ABIN715691)

抗原

See all CARD11 抗体
CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

适用

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宿主

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克隆类型

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多克隆

标记

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This CARD11 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 301-400

    预测反应

    Human,Mouse,Rat,Dog,Cow,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CARD11

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

    别名

    Card11

    背景

    Synonyms: Bcl10 interacting maguk protein 3, BIMP 3, BIMP3, CAR11_HUMAN, CARD 11, CARD containing MAGUK protein 3, Card maguk protein 1, CARD-containing MAGUK protein 1, CARD11, CARD11 protein, Carma 1, CARMA1, Caspase recruitment domain containing protein 11, Caspase recruitment domain family member 11, Caspase recruitment domain-containing protein 11, MGC133069.

    Background: The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

    基因ID

    84433

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, BCR Signaling
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