SLITRK1 抗体 (PE)
Quick Overview for SLITRK1 抗体 (PE) (ABIN715566)
抗原
See all SLITRK1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Excitation / Emission Wavelengths: 565nm/578nm
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交叉反应
- 大鼠, 小鸡, 犬, 猪, 牛
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纯化方法
- purified by Protein A
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免疫原
- KLH conjugated synthetic peptide derived from human Slitrk1
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亚型
- IgG
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说明
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Excitation / Emission wavelength: 496nm / 578nm
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 µg/µL
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缓冲液
- Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 4 °C for 12 months
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有效期
- 12 months
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- SLITRK1 (SLIT and NTRK-Like Family, Member 1 (SLITRK1))
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别名
- Slitrk1
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背景
- Slitrk1 is a member of a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk1 is expressed primarily in mature neurons. Overexpression of Slitrk1 in transfected neuronal cells induced unipolar neurites, while expression of the other Slitrk proteins inhibited neurite outgrowth, suggesting that these proteins are involved in the control of neurite outgrowth. While Slitrk1 variants have been suggested associated with Touretteメs Syndrome, it is thought to play only a minor role if at all.
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分子量
- 78-88kDa
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基因ID
- 114798
抗原
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