P4HB 抗体 (AA 309-508)
Quick Overview for P4HB 抗体 (AA 309-508) (ABIN7193950)
抗原
See all P4HB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 309-508
-
原理
- P4HB Antibody
-
纯化方法
- Purified antibody
-
免疫原
- Purified recombinant fragment of human P4HB (AA:309-508) expressed in mammalian.
-
亚型
- IgG2a
-
-
-
-
应用备注
-
ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
- P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
-
别名
- P4HB
-
背景
-
This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq, Jul 2008]
-
分子量
- 57.1 kDa
-
UniProt
- P07237
-
途径
- Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism
抗原
-