TSG101 抗体 (AA 167-374)
Quick Overview for TSG101 抗体 (AA 167-374) (ABIN7193932)
抗原
See all TSG101 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 167-374
-
原理
- TSG101 Antibody
-
纯化方法
- Purified antibody
-
免疫原
- Purified recombinant fragment of human TSG101 (AA: 167-374) expressed in E. Coli.
-
亚型
- IgG1
-
-
-
-
应用备注
-
ELISA: 1/10000
FCM: 1/200 - 1/400
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
-
别名
- TSG101
-
背景
-
The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
-
分子量
- 44 kDa
-
基因ID
- 7251
-
UniProt
- Q99816
抗原
-