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IL-10RA 抗体 (AA 22-235)

This 小鼠 单克隆 anti-IL-10RA antibody (Clone 8A2A5) specifically detects IL-10RA in ELISA, FACS 和 ICC. The antibody is reactive with 人 samples.
产品编号 ABIN7193872
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL-10RA 抗体 (AA 22-235) (ABIN7193872)

抗原

See all IL-10RA (IL10RA) 抗体
IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

适用

  • 85
  • 48
  • 18
  • 5
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  • 2
  • 1
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宿主

  • 78
  • 22
  • 11
  • 2
小鼠

克隆类型

  • 78
  • 33
  • 1
单克隆

标记

  • 62
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This IL-10RA antibody is un-conjugated

应用范围

  • 73
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  • 15
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  • 10
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ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

8A2A5
  • 抗原表位

    • 11
    • 10
    • 7
    • 7
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    • 5
    • 4
    • 3
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    • 1
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    • 1
    • 1
    AA 22-235

    原理

    CD210 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human CD210 (AA: 22-235)) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/25 - 1/200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

    别名

    CD210

    背景

    The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

    分子量

    63 kDa

    基因ID

    3587

    UniProt

    Q13651

    途径

    Growth Factor Binding
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