PDLIM7 抗体 (AA 86-280)
Quick Overview for PDLIM7 抗体 (AA 86-280) (ABIN7193840)
抗原
See all PDLIM7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 86-280
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原理
- PDLIM7 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human PDLIM7 (AA: 86-280) expressed in HEK293-6e cells supernatant.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- PDLIM7 (PDZ and LIM Domain 7 (Enigma) (PDLIM7))
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别名
- PDLIM7
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背景
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The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.
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分子量
- 49.8 kDa
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UniProt
- Q9NR12
抗原
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