Prominin 2 抗体 (AA 301-400) (Cy7)
Quick Overview for Prominin 2 抗体 (AA 301-400) (Cy7) (ABIN715157)
抗原
See all Prominin 2 (PROM2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 301-400
-
交叉反应
- 人
-
预测反应
- Mouse,Rat,Dog,Pig
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human Prominin 2
-
亚型
- IgG
-
-
anti-Prominin 2 (PROM2) (AA 301-400) antibody
PROM2 适用: 人 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Prominin 2 (PROM2) antibodyPROM2 适用: 人 WB, IP 宿主: 小鼠 Monoclonal 5E5 unconjugated
anti-Prominin 2 (PROM2) (N-Term) antibodyPROM2 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Prominin 2 (PROM2) (AA 440-466) antibodyPROM2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- Prominin 2 (PROM2)
-
别名
- Prominin 2
-
背景
-
Synonyms: PROML2, Prominin-2, PROM-2, Prominin-like protein 2, hPROML2, PROM2, UNQ2521/PRO6014
Background: Prominin 2 is a 112 kDa glycoporotein structurally related to Prominin 1 (CD133) although amino acid similarity is not more than 30 % , but their genomic organization is strikingly similar. Like Prominin 1, the prominin 2 exhibit similar membrane topology with 5 trans-membrane domains and two large glycosylated extracellular domains. Similar to Prominin1 localization, the Prominin 2 is also associated with membrane protrusions of the epithelial cells from adult kidney, and all along the digestive track and other epithelial tissues.Prominin 2 expression is down-regulated in aggressive prostate cancer cell lines and transient transfection of PROML2 expression vectors has been shown to induce apoptosis in cultured prostate cancer cells, suggesting a tumor suppressive role for Prominin 2. Prominin 2 expression is likely to be involved in growth suppression in the prostate, and down-regulation of Prominin 2 may disrupt normal prostatic homeostasis and lead to uncontrolled prostatic growth.
-
基因ID
- 150696
-
UniProt
- Q8N271
抗原
-
