Prominin 2 抗体 (AA 301-400) (Biotin)
Quick Overview for Prominin 2 抗体 (AA 301-400) (Biotin) (ABIN715153)
抗原
See all Prominin 2 (PROM2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-400
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交叉反应
- 人
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预测反应
- Mouse,Rat,Dog,Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Prominin 2
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亚型
- IgG
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anti-Prominin 2 (PROM2) (AA 301-400) antibody
PROM2 适用: 人 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Prominin 2 (PROM2) antibodyPROM2 适用: 人 WB, IP 宿主: 小鼠 Monoclonal 5E5 unconjugated
anti-Prominin 2 (PROM2) (N-Term) antibodyPROM2 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Prominin 2 (PROM2) (AA 440-466) antibodyPROM2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- Prominin 2 (PROM2)
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别名
- Prominin 2
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背景
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Synonyms: PROML2, Prominin-2, PROM-2, Prominin-like protein 2, hPROML2, PROM2, UNQ2521/PRO6014
Background: Prominin 2 is a 112 kDa glycoporotein structurally related to Prominin 1 (CD133) although amino acid similarity is not more than 30 % , but their genomic organization is strikingly similar. Like Prominin 1, the prominin 2 exhibit similar membrane topology with 5 trans-membrane domains and two large glycosylated extracellular domains. Similar to Prominin1 localization, the Prominin 2 is also associated with membrane protrusions of the epithelial cells from adult kidney, and all along the digestive track and other epithelial tissues.Prominin 2 expression is down-regulated in aggressive prostate cancer cell lines and transient transfection of PROML2 expression vectors has been shown to induce apoptosis in cultured prostate cancer cells, suggesting a tumor suppressive role for Prominin 2. Prominin 2 expression is likely to be involved in growth suppression in the prostate, and down-regulation of Prominin 2 may disrupt normal prostatic homeostasis and lead to uncontrolled prostatic growth.
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基因ID
- 150696
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UniProt
- Q8N271
抗原
-
