KRT6A 抗体 (AA 253-352)
Quick Overview for KRT6A 抗体 (AA 253-352) (ABIN7193708)
抗原
See all KRT6A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 253-352
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原理
- KRT6A Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human KRT6A (AA: 253-352) expressed in E. Coli.
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亚型
- IgG2b
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- KRT6A (Keratin 6A (KRT6A))
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别名
- KRT6A
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背景
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The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified, the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathogens. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
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分子量
- 60 kDa
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基因ID
- 3853
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UniProt
- P02538
抗原
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