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KRT6A 抗体 (AA 253-352)

This anti-KRT6A antibody is a 小鼠 单克隆 antibody detecting KRT6A in WB, ELISA, FACS 和 ICC. Suitable for 人.
产品编号 ABIN7193708
发货至: 中国

Quick Overview for KRT6A 抗体 (AA 253-352) (ABIN7193708)

抗原

See all KRT6A 抗体
KRT6A (Keratin 6A (KRT6A))

适用

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宿主

  • 66
  • 33
  • 2
小鼠

克隆类型

  • 63
  • 38
单克隆

标记

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  • 9
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This KRT6A antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

7E3D1
  • 抗原表位

    • 9
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    AA 253-352

    原理

    KRT6A Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human KRT6A (AA: 253-352) expressed in E. Coli.

    亚型

    IgG2b
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    KRT6A (Keratin 6A (KRT6A))

    别名

    KRT6A

    背景

    The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified, the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathogens. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

    分子量

    60 kDa

    基因ID

    3853

    UniProt

    P02538
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