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ZAP70 抗体 (AA 169-390)

This anti-ZAP70 antibody is a 小鼠 单克隆 antibody detecting ZAP70 in WB, FACS 和 ELISA. Suitable for 人.
产品编号 ABIN7193547
发货至: 中国

Quick Overview for ZAP70 抗体 (AA 169-390) (ABIN7193547)

抗原

See all ZAP70 抗体
ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ZAP70 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), ELISA

克隆位点

1F3G9
  • 抗原表位

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    AA 169-390

    原理

    ZAP70 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human ZAP70 (AA: 169-390) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

    别名

    ZAP70

    背景

    This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

    分子量

    69.9 kDa

    基因ID

    7535

    UniProt

    P43403

    途径

    TCR Signaling, Ubiquitin Proteasome Pathway
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