L1CAM 抗体 (AA 20-197)
Quick Overview for L1CAM 抗体 (AA 20-197) (ABIN7193538)
抗原
See all L1CAM 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 20-197
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原理
- CD171 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human CD171 (AA: 20-197) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
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别名
- CD171
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背景
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The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.
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分子量
- 140 kDa
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基因ID
- 3897
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UniProt
- P32004
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途径
- Synaptic Membrane
抗原
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