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LIFR 抗体 (AA 22-441)

LIFR 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5D3G12 unconjugated
产品编号 ABIN7193531
发货至: 中国
  • 抗原 See all LIFR 抗体
    LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))
    抗原表位
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-441
    适用
    • 35
    • 11
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 45
    • 6
    小鼠
    克隆类型
    • 46
    • 5
    单克隆
    标记
    • 26
    • 9
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LIFR antibody is un-conjugated
    应用范围
    • 38
    • 14
    • 12
    • 9
    • 9
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    原理
    CD118 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human PLA2G7 (AA: 22-441) expressed in E. Coli.
    克隆位点
    5D3G12
    亚型
    IgG1
    Top Product
    Discover our top product LIFR Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))
    别名
    CD118 (LIFR 产品)
    背景

    This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5,8)(p13,q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding two different isoforms have been found for this gene.

    分子量
    123.7 kDa
    基因ID
    3977
    UniProt
    P42702
    途径
    JAK/STAT Signaling, Growth Factor Binding
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