PRNP 抗体 (AA 23-230)
Quick Overview for PRNP 抗体 (AA 23-230) (ABIN7193415)
抗原
See all PRNP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 23-230
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原理
- CD230 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human CD230 (AA: 23-230) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- PRNP (Prion Protein (PRNP))
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别名
- CD230
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背景
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The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
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分子量
- 27.7 kDa
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基因ID
- 5621
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UniProt
- P04156
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途径
- Transition Metal Ion Homeostasis, Activated T Cell Proliferation
抗原
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