KAT6B 抗体 (AA 1186-1318)
Quick Overview for KAT6B 抗体 (AA 1186-1318) (ABIN7193390)
抗原
See all KAT6B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1186-1318
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原理
- KAT6B Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human KAT6B (AA: 1186-1318) expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- KAT6B (K(lysine) Acetyltransferase 6B (KAT6B))
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别名
- KAT6B
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背景
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The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
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分子量
- 231.4 kDa
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基因ID
- 23522
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UniProt
- Q8WYB5
抗原
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