BCAM 抗体 (AA 32-197)
Quick Overview for BCAM 抗体 (AA 32-197) (ABIN7193338)
抗原
See all BCAM 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 32-197
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原理
- CD239 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human CD239 (AA: 32-197) expressed in E. Coli.
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亚型
- IgG2a
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))
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别名
- CD239
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背景
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This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.
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分子量
- 67.4 kDa
抗原
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