Macrophage Scavenger Receptor 1 抗体 (AA 275-451)
Quick Overview for Macrophage Scavenger Receptor 1 抗体 (AA 275-451) (ABIN7193254)
抗原
See all Macrophage Scavenger Receptor 1 (MSR1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 275-451
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原理
- CD204 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human CD204 (AA: 275-451) expressed in E. Coli.
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亚型
- IgG1
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anti-Macrophage Scavenger Receptor 1 (MSR1) (AA 211-320) antibody
MSR1 适用: 人, 小鼠, 绵羊 WB, ELISA, FACS, IHC (fro), IF (cc), IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) (N-Term) antibodyMSR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) antibodyMSR1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) antibodyMSR1 适用: 小鼠, Pig, Catfish (Ictalurus) WB, ELISA, FACS, IP, IHC (fro) 宿主: 大鼠 Monoclonal 2F8 unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) (AA 271-446) antibodyMSR1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) (AA 121-220) antibodyMSR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) (AA 85-134) antibodyMSR1 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Macrophage Scavenger Receptor 1 (MSR1)
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别名
- CD204
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背景
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This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages.
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分子量
- 49.8 kDa
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基因ID
- 4481
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UniProt
- P21757
抗原
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