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BCL10 抗体 (AA 98-234)

This anti-BCL10 antibody is a 小鼠 单克隆 antibody detecting BCL10 in ELISA 和 FACS. Suitable for 人.
产品编号 ABIN7193248
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
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Quick Overview for BCL10 抗体 (AA 98-234) (ABIN7193248)

抗原

See all BCL10 抗体
BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

适用

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宿主

  • 127
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小鼠

克隆类型

  • 92
  • 74
单克隆

标记

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This BCL10 antibody is un-conjugated

应用范围

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ELISA, Flow Cytometry (FACS)

克隆位点

3C11F4
  • 抗原表位

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    AA 98-234

    原理

    BCL10 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human BCL10 (AA: 98-234) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

    别名

    BCL10

    背景

    This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants.

    分子量

    26.3 kDa

    基因ID

    8915

    UniProt

    O95999

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
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