ITGAL 抗体 (AA 26-194)
Quick Overview for ITGAL 抗体 (AA 26-194) (ABIN7193238)
抗原
See all ITGAL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 26-194
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原理
- CD11a Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human CD11a (AA: 26-194) expressed in E. Coli.
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亚型
- IgG2a
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- ITGAL (Integrin alpha-L (ITGAL))
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别名
- CD11a
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背景
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ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.
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分子量
- 128.8 kDa
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基因ID
- 3683
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UniProt
- P20701
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途径
- Activated T Cell Proliferation, Integrin Complex
抗原
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