SLC8A2 抗体
Quick Overview for SLC8A2 抗体 (ABIN7192526)
抗原
See all SLC8A2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 人, 大鼠
-
纯化方法
- Antigen affinity purification
-
免疫原
- Synthetic peptide of Human SLC8A2
-
亚型
- IgG
-
-
anti-Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 2 (SLC8A2) (AA 601-700) antibody
SLC8A2 适用: 大鼠, 小鼠 WB, IF (cc), IF (p), ELISA, IHC (fro), IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 2 (SLC8A2) (AA 360-450) antibodySLC8A2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 2 (SLC8A2) (AA 486-499) antibodySLC8A2 适用: 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- ELISA:1:1000-1:2000, IHC:1:25-1:100,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- SLC8A2 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 2 (SLC8A2))
-
别名
- SLC8A2
-
背景
-
Background: Sodium/calcium exchanger proteins are integral membrane proteins primarily seen in cardiac cells. In cardiac myocytes, the concentration of Ca2+ alternates between low levels during relaxation and high levels during contraction. The Na+/Ca2+ exchanger 1 (NCX1) protein mediates Ca2+ extrusion from cardiac cells during relaxation. Four NCX1 isoforms (NCX1.1, NCX1.3, NCX1.7, and NCX1.10) result from alternate splicing. NCX1 mRNA is present at high levels in the heart, with lower levels present in the brain. NCX2 is most abundantly expressed in brain, in contrast the the broader distribution of NCX1, which is also expressed in heart, kidney, lung, smooth and skeletal muscle. The difference in expression for the transporter subtypes is believed to reflect differences in their functional roles. Regulation mechanisms for these exchanger proteins have not been fully characterized.
Aliases: SLC8A2 antibody, KIAA1087 antibody, NCX2 antibody, Sodium/calcium exchanger 2 antibody, Na(+)/Ca(2+)-exchange protein 2 antibody, Solute carrier family 8 member 2 antibody
-
UniProt
- Q9UPR5
抗原
-
