DLC1 抗体 (AA 1-80) (Cy3)
Quick Overview for DLC1 抗体 (AA 1-80) (Cy3) (ABIN714959)
抗原
See all DLC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-80
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预测反应
- Human,Mouse,Rat,Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human DLC1
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亚型
- IgG
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anti-Deleted in Liver Cancer 1 (DLC1) (N-Term) antibody
Verified DLC1 适用: 人, 小鼠 IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (N-Term) antibodyDLC1 适用: 人, 小鼠, 大鼠 IHC, WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (N-Term) antibodyDLC1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (AA 204-463) antibodyDLC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (AA 1-1528) antibodyDLC1 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (AA 1-1528) antibodyDLC1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (AA 1224-1273) antibodyDLC1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (C-Term) antibodyDLC1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (AA 61-110) antibodyDLC1 适用: 人, 小鼠, 大鼠 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- DLC1 (Deleted in Liver Cancer 1 (DLC1))
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别名
- DLC1
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背景
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Synonyms: LC8, PIN, DLC1, DLC8, LC8a, DNCL1, hdlc1, DNCLC1, Dynein light chain 1, cytoplasmic, 8 kDa dynein light chain, Dynein light chain LC8-type 1, Protein inhibitor of neuronal nitric oxide synthase, DYNLL1
Background: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Binds and inhibits the catalytic activity of neuronal nitric oxide synthase. Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1. Regulates apoptotic activities of BCL2L11 by sequestering it to microtubules. Upon apoptotic stimuli the BCL2L11-DYNLL1 complex dissociates from cytoplasmic dynein and translocates to mitochondria and sequesters BCL2 thus neutralizing its antiapoptotic activity.
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基因ID
- 8655
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UniProt
- P63167
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途径
- Tube Formation, Positive Regulation of Endopeptidase Activity
抗原
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