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BAG5 抗体 (AA 101-200) (Cy5)

This anti-BAG5 antibody is a 兔 多克隆 antibody detecting BAG5 in IF (cc) 和 IF (p). Suitable for 小鼠.
产品编号 ABIN714945
发货至: 中国

Quick Overview for BAG5 抗体 (AA 101-200) (Cy5) (ABIN714945)

抗原

See all BAG5 抗体
BAG5 (BCL2-Associated Athanogene 5 (BAG5))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This BAG5 antibody is conjugated to Cy5

应用范围

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Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 101-200

    交叉反应

    小鼠

    预测反应

    Human,Rat,Dog,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human BAG5

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    BAG5 (BCL2-Associated Athanogene 5 (BAG5))

    别名

    BAG5

    背景

    Synonyms: BAG family molecular chaperone regulator 5, BAG 5, BAG-5, BCL2 associated athanogene 5, KIAA0873, BAG5_HUMAN.

    Background: BAG5 is a member of the BAG1 related protein family. BAG1 is an anti apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL 2, Raf protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. A BAG domain near the C terminus, may bind and inhibit the chaperone activity of Hsc70/Hsp70. It has been hypothesized that the BAG5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70?s anti apoptotic function. It is believed that BAG5 will play an important role in the mechanisms of neuronal death. BAG5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/modulation of other BAG containing proteins via BAG-BAGheterodimerization.

    基因ID

    9529

    途径

    SARS-CoV-2 Protein Interactome
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