EID3 抗体
Quick Overview for EID3 抗体 (ABIN7190538)
抗原
See all EID3 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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纯化方法
- Antigen affinity purification
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免疫原
- Synthetic peptide of Human EID3
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亚型
- IgG
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应用备注
- ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- EID3 (EP300 Interacting Inhibitor of Differentiation 3 (EID3))
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别名
- EID3
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背景
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Background: EID3 is highly expressed in testis and shows homology to a region of EID1 implicated in binding to CBP/p300. EID3 acts as a potent inhibitor of nuclear receptor transcriptional activity by a mechanism that is independent of direct interactions with nuclear receptors, including SHP. Furthermore, EID3 directly binds to and blocks the SRC-1 interacting domain of CBP, which has been implicated to act as the interaction surface for nuclear receptor co-activators. Consistent with this idea, EID3 prevents recruitment of CBP to a natural nuclear receptor-regulated promoter.
Aliases: E1A-like inhibitor of differentiation 3 antibody, EID 3 antibody, EID-1-like inhibitor of differentiation 3 antibody, EID-3 antibody, EID3 antibody, EID3_HUMAN antibody, EP300 interacting inhibitor of differentiation 3 antibody, EP300-interacting inhibitor of differentiation 3 antibody, FLJ25832 antibody, Non-SMC element 4, S. cerevisiae, homolog of, B antibody, Non-structural maintenance of chromosomes element 4 homolog B antibody, NSE4B antibody, NSMCE4B antibody
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UniProt
- Q8N140
抗原
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