ITGAV/ITGB6 抗体
(4 references)Our Local Distributor
北京 101111
Quick Overview for ITGAV/ITGB6 抗体 (ABIN714806)
抗原
适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Integrin Alpha V + Beta 6
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Dupuytren's Disease Is Mediated by Insufficient TGF-β1 Release and Degradation." in: International journal of molecular sciences, Vol. 24, Issue 20, (2023) (PubMed).
: "Effect of human amniotic epithelial cells on pro-fibrogenic resident hepatic cells in a rat model of liver fibrosis." in: Journal of cellular and molecular medicine, Vol. 22, Issue 2, pp. 1202-1213, (2017) (PubMed).
: "A near-infrared phthalocyanine dye-labeled agent for integrin ?v?6-targeted theranostics of pancreatic cancer." in: Biomaterials, Vol. 53, pp. 229-38, (2015) (PubMed).
: "Scutellarin inhibits the growth and invasion of human tongue squamous carcinoma through the inhibition of matrix metalloproteinase-2 and -9 and αvβ6 integrin." in: International journal of oncology, Vol. 42, Issue 5, pp. 1674-81, (2013) (PubMed).
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: "Dupuytren's Disease Is Mediated by Insufficient TGF-β1 Release and Degradation." in: International journal of molecular sciences, Vol. 24, Issue 20, (2023) (PubMed).
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- ITGAV/ITGB6 (Integrin alpha V, Integrin beta 6 (ITGAV/ITGB6))
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别名
- Integrin Alpha V + Beta 6
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背景
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Synonyms: CD51, Integrin alpha-V light chain, integrin, alpha V vitronectin receptor, alpha polypeptide, antigen CD51, Integrin, alpha V, Integrin, beta 6, ITAV_HUMAN, ITGAV, ITGB6, Vitronectin receptor subunit alpha.
Background: Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin alpha-v beta-6 is upregulated in cancers and during tissue remodelling but is absent from resting adult tissues. Integrin alpha-v beta-6 promotes invasion and correlates with poor survival and therefore makes a promising therapeutic target.
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基因ID
- 36853694
抗原
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