BRWD1 抗体
Quick Overview for BRWD1 抗体 (ABIN7190020)
抗原
See all BRWD1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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纯化方法
- Antigen affinity purification
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免疫原
- Synthetic peptide of Human BRWD1
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亚型
- IgG
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应用备注
- ELISA:1:2000-1:5000, IHC:1:20-1:100,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BRWD1 (Bromodomain and WD Repeat Domain Containing 1 (BRWD1))
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别名
- BRWD1
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背景
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Background: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.
Aliases: bromodomain and WD repeat domain containing 1
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UniProt
- Q9NSI6
抗原
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