APOB 抗体
Quick Overview for APOB 抗体 (ABIN7189848)
抗原
See all APOB 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Antigen affinity purification
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免疫原
- Synthetic peptide of Human APOB
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亚型
- IgG
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应用备注
- ELISA:1:1000-1:5000, IHC:1:15-1:50,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- APOB (Apolipoprotein B (APOB))
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别名
- APOB
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背景
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Background: This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.
Aliases: Apo B 100 antibody, Apo B antibody, Apo B-100 antibody, Apo B-48 antibody, Apo B100 antibody, Apo B48 antibody, ApoB 100 antibody, ApoB 48 antibody, APOB antibody, APOB_HUMAN antibody, Apolipoprotein B (including Ag(x) antigen) antibody, Apolipoprotein B 100 antibody, Apolipoprotein B 48 antibody, Apolipoprotein B antibody, Apolipoprotein B-48 antibody, Apolipoprotein B100 antibody, Apolipoprotein B48 antibody, FLDB antibody, LDLCQ4 antibody
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UniProt
- P04114
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途径
- Lipid Metabolism
抗原
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