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APOB 抗体

The 兔 多克隆 anti-APOB antibody (ABIN7189848) specifically detects APOB in IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7189848
发货至: 中国
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Quick Overview for APOB 抗体 (ABIN7189848)

抗原

See all APOB 抗体
APOB (Apolipoprotein B (APOB))

适用

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宿主

  • 79
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克隆类型

  • 83
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多克隆

标记

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This APOB antibody is un-conjugated

应用范围

  • 86
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Immunohistochemistry (IHC), ELISA
  • 原理

    APOB Antibody

    交叉反应

    小鼠, 大鼠

    纯化方法

    Antigen affinity purification

    免疫原

    Synthetic peptide of Human APOB

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

     pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    APOB (Apolipoprotein B (APOB))

    别名

    APOB

    背景

    Background: This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.

    Aliases: Apo B 100 antibody, Apo B antibody, Apo B-100 antibody, Apo B-48 antibody, Apo B100 antibody, Apo B48 antibody, ApoB 100 antibody, ApoB 48 antibody, APOB antibody, APOB_HUMAN antibody, Apolipoprotein B (including Ag(x) antigen) antibody, Apolipoprotein B 100 antibody, Apolipoprotein B 48 antibody, Apolipoprotein B antibody, Apolipoprotein B-48 antibody, Apolipoprotein B100 antibody, Apolipoprotein B48 antibody, FLDB antibody, LDLCQ4 antibody

    UniProt

    P04114

    途径

    Lipid Metabolism
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