ANKRD28 抗体
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北京 101111
Quick Overview for ANKRD28 抗体 (ABIN7189809)
抗原
See all ANKRD28 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ANKRD28 Antibody
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交叉反应
- 小鼠
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纯化方法
- Antigen affinity purification
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免疫原
- Synthetic peptide of Human ANKRD28
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亚型
- IgG
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anti-Ankyrin Repeat Domain 28 (ANKRD28) (AA 430-530) antibody
ANKRD28 适用: 大鼠 WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ankyrin Repeat Domain 28 (ANKRD28) (AA 1-300) antibodyANKRD28 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ANKRD28 (Ankyrin Repeat Domain 28 (ANKRD28))
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别名
- ANKRD28
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背景
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Background: Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation. ANKRD28 selectively regulated phosphorylation of hnRNP-K at ser284, an effect that was enhanced in vivo by an S1013A/S1017A double mutant, suggesting that ANKRD28 targets PP1 in a regulated manner to dephosphorylate hnRNP-K selectively at ser284.
Aliases: ANKRD28 antibody, KIAA0379Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A antibody, PP6-ARS-A antibody, Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A antibody, Ankyrin repeat domain-containing protein 28 antibody, Phosphatase interactor targeting protein hnRNP K antibody, PITK antibody
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UniProt
- O15084
抗原
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