Exendin 4 抗体
Quick Overview for Exendin 4 抗体 (ABIN7189562)
抗原
See all Exendin 4 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- Gila monster
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纯化方法
- Antigen affinity purification
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免疫原
- Synthetic peptide of Heloderma suspectum Exendin 4
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亚型
- IgG
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应用备注
- ELISA:1:1000-1:2000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Exendin 4
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别名
- Exendin-4
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背景
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Background: Exendin 4 is a 39 amino acid peptide found in venom from the Gila monster Helicoderma suspectum. It is a member of the glucagon secretin family of peptide hormones and neuropeptides. Exendin 4 is a potent agonist of the GLP1 receptor and hence a potent stimulator of insulin secretion. It stimulates insulin synthesis and secretion, protects against beta-cell apoptosis in response to different insults, and promotes beta-cell proliferation. It also promotes satiety, reduces food intake, reduces fat deposition, reduces body weight and inhibits gastric emptying. Interacts with GLP-1 receptor (GLP1R). Induces hypotension that is mediated by relaxation of cardiac smooth muscle.
Aliases: Exendin-4 antibody, Exenatide antibody
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UniProt
- P26349
抗原
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