SERPINA4 抗体 (AA 161-220)
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北京 101111
Quick Overview for SERPINA4 抗体 (AA 161-220) (ABIN714731)
抗原
See all SERPINA4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 161-220
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交叉反应
- 小鼠
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预测反应
- Human,Rat
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human KLST/Kallistatin (161-220aa)
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Polymorphisms at the F12 and KLKB1 loci have significant trait association with activation of the renin-angiotensin system." in: BMC medical genetics, Vol. 17, pp. 21, (2016) (PubMed).
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: "Polymorphisms at the F12 and KLKB1 loci have significant trait association with activation of the renin-angiotensin system." in: BMC medical genetics, Vol. 17, pp. 21, (2016) (PubMed).
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- SERPINA4 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 (SERPINA4))
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别名
- KLST
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背景
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Synonyms: Serpin peptidase inhibitor clade A member 4, Kallikrein binding protein, Kallikrein inhibitor, Protease inhibitor 4, Serpin A4, KAL, Kallikrein binding protein, Kallikrein inhibitor, KBP, KLST, KST, MGC108582, PI4, Protease inhibitor 4, Serpin A4, Serpin peptidase inhibitor clade A member 4, SERPINA4, KAIN_HUMAN.
Background: Kallistatin is a serine proteinase inhibitor which binds to tissue kallikrein and inhibits its amidolytic and kininogenase activity. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.
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基因ID
- 5267
抗原
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