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HSD11B1 抗体 (N-Term)

This 兔 多克隆 anti-HSD11B1 antibody specifically detects HSD11B1 in WB, ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7184465
发货至: 中国
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Quick Overview for HSD11B1 抗体 (N-Term) (ABIN7184465)

抗原

See all HSD11B1 抗体
HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))

适用

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宿主

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克隆类型

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多克隆

标记

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This HSD11B1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
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    N-Term

    原理

    HSD11B1 Antibody

    交叉反应

    小鼠

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from N-terminal of Human HSD11B1.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))

    别名

    HSD11B1

    背景

    Background: Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol By similarity.

    Tannin G.M., J. Biol. Chem. 266:16653-16658(1991).
    Draper N., J. Clin. Endocrinol. Metab. 87:4984-4990(2002).
    Ota T., Nat. Genet. 36:40-45(2004) .

    Aliases: 11 beta HSD 1 antibody, 11 beta HSD1 antibody, 11 beta hydroxysteroid dehydrogenase 1 antibody, 11 DH antibody, 11-beta hydroxysteroid dehydrogenase, type 1 antibody, 11-beta-HSD1 antibody, 11-beta-hydroxysteroid dehydrogenase 1 antibody, 11-DH antibody, 11DH antibody, Corticosteroid 11 beta dehydrogenase isozyme 1 antibody, Corticosteroid 11-beta-dehydrogenase isozyme 1 antibody, CORTRD2 antibody, DHI1_HUMAN antibody, HDL antibody, HSD 11 antibody, HSD11 antibody, HSD11B antibody, HSD11B1 antibody, HSD11L antibody, Hydroxysteroid (11 beta) dehydrogenase antibody, Hydroxysteroid (11 beta) dehydrogenase 1 antibody, MGC13539 antibody, SDR26C1 antibody, short chain dehydrogenase/reductase family 26C, member 1 antibody

    UniProt

    P28845

    途径

    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Carbohydrate Metabolic Process
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