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CNOT7 抗体 (N-Term)

The 兔 多克隆 anti-CNOT7 antibody is suitable to detect CNOT7 in samples from 人. It has been validated for WB 和 ELISA.
产品编号 ABIN7184433
发货至: 中国
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Quick Overview for CNOT7 抗体 (N-Term) (ABIN7184433)

抗原

See all CNOT7 抗体
CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

适用

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宿主

  • 33
  • 7

克隆类型

  • 34
  • 6
多克隆

标记

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This CNOT7 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

    • 7
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    N-Term

    原理

    CNOT7 Antibody

    交叉反应

    小鼠

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from N-terminal of Human CNOT7.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

    别名

    CNOT7

    背景

    Background: Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.

    Bogdan J.A., Biochem. J. 336:471-481(1998).
    The MGC Project Team, Genome Res. 14:2121-2127(2004).

    Aliases: BTG1 binding factor 1 antibody, BTG1-binding factor 1 antibody, CAF 1 antibody, CAF-1 antibody, CAF1 antibody, Carbon catabolite repressor protein (CCR4) associative factor 1 antibody, CCR4 associated factor 1 antibody, CCR4 NOT transcription complex subunit 7 antibody, CCR4-associated factor 1 antibody, CCR4-NOT transcription complex subunit 7 antibody, CNOT 7 antibody, Cnot7 antibody, CNOT7_HUMAN antibody, hCAF 1 antibody, hCAF1 antibody

    UniProt

    Q9UIV1

    途径

    Ribonucleoprotein Complex Subunit Organization
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