CNOT7 抗体 (N-Term)
Quick Overview for CNOT7 抗体 (N-Term) (ABIN7184433)
抗原
See all CNOT7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 人, 小鼠
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from N-terminal of Human CNOT7.
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亚型
- IgG
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应用备注
- WB:1:500-1:3000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))
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别名
- CNOT7
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背景
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Background: Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.
Bogdan J.A., Biochem. J. 336:471-481(1998).
The MGC Project Team, Genome Res. 14:2121-2127(2004).Aliases: BTG1 binding factor 1 antibody, BTG1-binding factor 1 antibody, CAF 1 antibody, CAF-1 antibody, CAF1 antibody, Carbon catabolite repressor protein (CCR4) associative factor 1 antibody, CCR4 associated factor 1 antibody, CCR4 NOT transcription complex subunit 7 antibody, CCR4-associated factor 1 antibody, CCR4-NOT transcription complex subunit 7 antibody, CNOT 7 antibody, Cnot7 antibody, CNOT7_HUMAN antibody, hCAF 1 antibody, hCAF1 antibody
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UniProt
- Q9UIV1
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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