TUT1 抗体
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北京 101111
Quick Overview for TUT1 抗体 (ABIN7184310)
抗原
See all TUT1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TUT1 Antibody
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from internal of Human TUT1.
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亚型
- IgG
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anti-Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1) (N-Term) antibody
TUT1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1) (AA 253-302) antibodyTUT1 适用: 人, 犬, Cow, 豚鼠, 马, 猴, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1) (N-Term) antibodyTUT1 适用: 人, 小鼠, 犬, 豚鼠, 大鼠, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1) (AA 829-878) antibodyTUT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1) (N-Term) antibodyTUT1 适用: 人, 小鼠, 犬, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1) (AA 291-340) antibodyTUT1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1) (N-Term) antibodyTUT1 适用: 人, 小鼠, 犬, Cow, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TUT1 (Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1))
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别名
- TUT1
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背景
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Background: Poly(A) polymerase that creates the 3'-poly(A) tail of specific pre-mRNAs. Localizes to nuclear speckles together with PIP5K1A and mediates polyadenylation of a select set of mRNAs, such as HMOX1. In addition to polyadenylation, it is also required for the 3'-end cleavage of pre-mRNAs: binds to the 3'UTR of targeted pre-mRNAs and promotes the recruitment and assembly of the CPSF complex on the 3'UTR of pre-mRNAs. In addition to adenylyltransferase activity, also has uridylyltransferase activity. However, the ATP ratio is higher than UTP in cells, suggesting that it functions primarily as a poly(A) polymerase. Acts as a specific terminal uridylyltransferase for U6 snRNA in vitro: responsible for a controlled elongation reaction that results in the restoration of the four 3'-terminal UMP-residues found in newly transcribed U6 snRNA. Not involved in replication-dependent histone mRNA degradation.
Ota T., Nat. Genet. 36:40-45(2004).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Trippe R.,RNA 12:1494-1504(2006).Aliases: alpha regulated poly(A) polymerase antibody, nuclear speckle targeted phosphatidylinositol 4 phosphate 5 kinase type I antibody, nuclear speckle targeted PIPK1A regulated poly(A) polymerase antibody, PAP associated domain containing 2 antibody, PAPD2 antibody, poly(A) polymerase associated domain containing 2 antibody, RBM21 antibody, RNA binding motif protein 21 antibody, RNA-binding motif protein 21 antibody, RNA-binding protein 21 antibody, Speckle targeted PIP5K1A-regulated poly(A) polymerase antibody, Star-PAP antibody, STARPAP antibody, STPAP_HUMAN antibody, terminal uridylyl transferase 1, U6 snRNA specific antibody, TUT1 antibody, TUTase antibody, U6 snRNA specific terminal uridylyltransferase 1 antibody, U6 snRNA-specific terminal uridylyltransferase 1 antibody, U6 TUTase antibody, U6-TUTase antibody, URLC6 antibody
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UniProt
- Q9H6E5
抗原
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