TSEN54 抗体
Quick Overview for TSEN54 抗体 (ABIN7184298)
抗原
See all TSEN54 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from internal of Human TSEN54.
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亚型
- IgG
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anti-tRNA Splicing Endonuclease 54 (TSEN54) (Internal Region) antibody
TSEN54 适用: 人, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-tRNA Splicing Endonuclease 54 (TSEN54) (AA 427-525) antibodyTSEN54 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-tRNA Splicing Endonuclease 54 (TSEN54) (AA 1-300) antibodyTSEN54 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB:1:500-1:3000, IHC:1:50-1:100,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TSEN54 (tRNA Splicing Endonuclease 54 (TSEN54))
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别名
- TSEN54
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背景
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Background: Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.
Zody M.C., Nature 440:1045-1049(2006).
Paushkin S.V., Cell 117:311-321(2004).
Ota T., Nat. Genet. 36:40-45(2004).Aliases: HsSen54 antibody, PCH2A antibody, PCH4 antibody, sen54 antibody, SEN54 homolog antibody, SEN54_HUMAN antibody, SEN54L antibody, tRNA-intron endonuclease SEN54 antibody, tRNA-splicing endonuclease subunit SEN54 antibody, Tsen54 antibody, TSEN54 tRNA splicing endonuclease subunit antibody
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UniProt
- Q7Z6J9
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途径
- Synaptic Membrane
抗原
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