TEAD3 抗体
Quick Overview for TEAD3 抗体 (ABIN7184247)
抗原
See all TEAD3 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from internal of Human TEAD3.
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亚型
- IgG
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应用备注
- WB:1:500-1:3000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TEAD3 (TEA Domain Family Member 3 (TEAD3))
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别名
- TEAD3
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背景
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Background: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer.
Jacquemin P., J. Biol. Chem. 272:12928-12937(1997).
Mungall A.J., Nature 425:805-811(2003).
Zhao B., Genes Dev. 22:1962-1971(2008).Aliases: DTEF 1 antibody, DTEF-1 antibody, DTEF1 antibody, ETFR 1 antibody, ETFR1 antibody, TEA domain family member 3 antibody, TEA domain family member 5 antibody, TEAD 3 antibody, TEAD-3 antibody, Tead3 antibody, TEAD3_HUMAN antibody, TEAD5 antibody, TEF 5 antibody, TEF5 antibody, Transcriptional enhancer factor 5 antibody, Transcriptional enhancer factor TEF 5 (DTEF 1) antibody, Transcriptional enhancer factor TEF 5 antibody, Transcriptional enhancer factor TEF-5 antibody
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UniProt
- Q99594
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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