STK36 抗体
Quick Overview for STK36 抗体 (ABIN7184207)
抗原
See all STK36 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from internal of Human STK36.
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亚型
- IgG
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anti-serine/threonine Kinase 36 (STK36) (AA 1-1315) antibody
STK36 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 36 (STK36) (Internal Region) antibodySTK36 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 36 (STK36) (AA 1-1315) antibodySTK36 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-serine/threonine Kinase 36 (STK36) (AA 250-450) antibodySTK36 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 36 (STK36) (AA 387-436) antibodySTK36 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB:1:500-1:3000, IHC:1:50-1:100,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- STK36 (serine/threonine Kinase 36 (STK36))
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别名
- STK36
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背景
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Background: Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur. Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Essential for construction of the central pair apparatus of motile cilia.
Murone M., Nat. Cell Biol. 2:310-312(2000).
Nagase T., DNA Res. 6:337-345(1999).
Hillier L.W., Nature 434:724-731(2005).Aliases: FU antibody, Fused homolog antibody, KIAA1278 antibody, Serine/threonine kinase 36, fused homolog antibody, Serine/threonine protein kinase 36 fused homolog antibody, Serine/threonine-protein kinase 36 antibody, STK36 antibody, STK36_HUMAN antibody
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UniProt
- Q9NRP7
抗原
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