POLR3B 抗体
Quick Overview for POLR3B 抗体 (ABIN7184076)
抗原
See all POLR3B 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from internal of Human RPC2.
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亚型
- IgG
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anti-Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) (AA 2-100) antibody
POLR3B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G10 unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) (AA 831-939) antibodyPOLR3B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) (C-Term) antibodyPOLR3B 适用: 人, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) (AA 866-915) antibodyPOLR3B 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 斑马鱼, Pig, 马, 猴, 豚鼠, Drosophila melanogaster, 小鸡, Hamster, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) (AA 680-900) antibodyPOLR3B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) (C-Term) antibodyPOLR3B 适用: 人, 小鼠, 大鼠, Drosophila melanogaster WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) antibodyPOLR3B 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 斑马鱼, Pig, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) (C-Term) antibodyPOLR3B 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 斑马鱼, 马, 豚鼠, Saccharomyces cerevisiae, 山羊 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB:1:500-1:3000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- POLR3B (Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B))
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别名
- POLR3B
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背景
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Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft By similarity. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.
Hu P., Mol. Cell. Biol. 22:8044-8055(2002).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Ota T., Nat. Genet. 36:40-45(2004).Aliases: C128 antibody, DNA directed RNA polymerase III 127.6 kDa polypeptide antibody, DNA directed RNA polymerase III subunit B antibody, DNA-directed RNA polymerase III 127.6 kDa polypeptide antibody, DNA-directed RNA polymerase III subunit B antibody, DNA-directed RNA polymerase III subunit RPC2 antibody, FLJ10388 antibody, polr3b antibody, Polymerase (RNA) III (DNA directed) polypeptide B antibody, RNA polymerase III subunit C2 antibody, RNA polymerase III subunit RPC2 antibody, RPC2 antibody, RPC2_HUMAN antibody
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UniProt
- Q9NW08
抗原
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