PPP1R16B 抗体
Quick Overview for PPP1R16B 抗体 (ABIN7183999)
抗原
See all PPP1R16B 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 人
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from internal of Human PPP1R16B.
-
亚型
- IgG
-
-
-
-
应用备注
- WB:1:500-1:3000,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- PPP1R16B (Protein Phosphatase 1, Regulatory Subunit 16B (PPP1R16B))
-
别名
- PPP1R16B
-
背景
-
Background: Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function. Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation. Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1. Involved in the regulation of endothelial cell filopodia extension. May be a downstream target for TGF-beta1 signaling cascade in endothelial cells.
Cao W., Am. J. Physiol. 283:C327-C337(2002).
Nagase T., DNA Res. 5:355-364(1998).
Nakajima D., DNA Res. 9:99-106(2002).Aliases: ANKRD4 antibody, Ankyrin repeat domain containing protein 4 antibody, ankyrin repeat domain protein 4 antibody, Ankyrin repeat domain-containing protein 4 antibody, CAAX box protein TIMAP antibody, hTIMAP antibody, KIAA0823 antibody, PP16B_HUMAN antibody, PPP1R16B antibody, Protein phosphatase 1 regulatory inhibitor subunit 16B antibody, protein phosphatase 1, regulatory (inhibitor) subunit 16B antibody, TGF beta inhibited membrane associated protein antibody, TGF-beta-inhibited membrane-associated protein antibody, TIMAP antibody
-
UniProt
- Q96T49
抗原
-