GADD45GIP1 抗体
Quick Overview for GADD45GIP1 抗体 (ABIN7183563)
抗原
See all GADD45GIP1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- GADD45GIP1 Antibody
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from internal of Human GADD45GIP1.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))
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别名
- GADD45GIP1
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背景
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Background: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
Goernemann J., Virology 303:69-78(2002).
Chung H.K., J. Biol. Chem. 278:28079-28088(2003).
The MGC Project Team, Genome Res. 14:2121-2127(2004).Aliases: 39S ribosomal protein L59 mitochondrial antibody, CKBBP2 antibody, CKbetaBP2 antibody, CKII beta associating protein antibody, CKII beta binding protein 2 antibody, CKII beta-associating protein antibody, CR6 interacting factor 1 antibody, CR6-interacting factor 1 antibody, CRIF1 antibody, G45IP_HUMAN antibody, GADD45G interacting protein 1 antibody, Gadd45gip1 antibody, Growth arrest and DNA damage inducible GADD45G interacting protein antibody, growth arrest and DNA damage inducible, gamma interacting protein 1 antibody, Growth arrest and DNA damage-inducible proteins-interacting protein 1 antibody, MGC4667 antibody, MGC4758 antibody, MRP L59 antibody, p53 responsive gene 6 antibody, p53 responsive gene 6 protein antibody, p53-responsive gene 6 protein antibody, Papillomavirus L2 interacting nuclear protein 1 antibody, Papillomavirus L2-interacting nuclear protein 1 antibody, PLINP 1 antibody, PLINP antibody, PLINP-1 antibody, PLINP1 antibody, PRG6 antibody
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UniProt
- Q8TAE8
抗原
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