CHAF1A 抗体
Quick Overview for CHAF1A 抗体 (ABIN7183230)
抗原
See all CHAF1A 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from internal of Human CAF1A.
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亚型
- IgG
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anti-Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A) (AA 21-120) antibody
CHAF1A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C2 unconjugated
anti-Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A) (Internal Region) antibodyCHAF1A 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A) (AA 840-904) antibodyCHAF1A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A) (AA 1-200) antibodyCHAF1A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A) (Internal Region) antibodyCHAF1A 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A) antibodyKD Validated CHAF1A 适用: 人 WB, IP, IHC, IF, ICC, FACS 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
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应用备注
- WB:1:500-1:3000, IHC:1:50-1:200, IF:1:100-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CHAF1A (Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A))
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别名
- CHAF1A
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背景
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Background: Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA, histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci By similarity. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.
Dong H., Gene 264:187-196(2001) [PubMed: 11250073].
Grimwood J., Nature 428:529-535(2004) [PubMed: 15057824].
Kaufman P.D., Cell 81:1105-1114(1995) [PubMed: 7600578].
Aliases: CAF 1 antibody, CAF 1 subunit A antibody, CAF antibody, CAF I 150 kDa subunit antibody, CAF I p150 antibody, CAF-1 subunit A antibody, CAF-I 150 kDa subunit antibody, CAF-I p150 antibody, CAF1 antibody, CAF1A_HUMAN antibody, CAF1B antibody, CAF1P150 antibody, CHAF1A antibody, Chromatin assembly factor 1 subunit A antibody, Chromatin Assembly Factor 1 Subunit A p150 antibody, Chromatin assembly factor I (150 kDa) antibody, Chromatin assembly factor I 150 kDa antibody, Chromatin assembly factor I p150 subunit antibody, DCAF1 antibody, hp150 antibody, MGC71229 antibody, P150 antibody
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UniProt
- Q13111
抗原
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