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beta Synuclein 抗体

This 兔 多克隆 anti-beta Synuclein antibody specifically detects beta Synuclein in WB, ELISA, IHC 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7182802
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for beta Synuclein 抗体 (ABIN7182802)

抗原

See all beta Synuclein (SNCB) 抗体
beta Synuclein (SNCB) (Synuclein, beta (SNCB))

适用

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宿主

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克隆类型

  • 50
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多克隆

标记

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This beta Synuclein antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    SNCB Antibody

    交叉反应

    小鼠, 大鼠

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from Human Synuclein beta antibody.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    beta Synuclein (SNCB) (Synuclein, beta (SNCB))

    别名

    SNCB

    背景

    Background: Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.

    Yuxin Fan, Hum. Mol. Genet., Oct 2006, 15: 3002 - 3011.
    Makoto Hashimoto, J. Biol. Chem., May 2004, 279: 23622 - 23629.
    Cristine Alves da Costa, J. Biol. Chem., Sep 2003, 278: 37330 - 37335.
    Heather Snyder, J. Biol. Chem., Mar 2005, 280: 7562 - 7569.

    Aliases: 14 kDa brain-specific protein antibody, Beta-synuclein antibody, Phosphoneuroprotein 14 antibody, PNP14 antibody, Sncb antibody, Synuclein beta antibody, SYUB_HUMAN antibody

    UniProt

    Q16143
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