beta Synuclein 抗体
Quick Overview for beta Synuclein 抗体 (ABIN7182802)
抗原
See all beta Synuclein (SNCB) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from Human Synuclein beta antibody.
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亚型
- IgG
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应用备注
- WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- beta Synuclein (SNCB) (Synuclein, beta (SNCB))
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别名
- SNCB
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背景
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Background: Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.
Yuxin Fan, Hum. Mol. Genet., Oct 2006, 15: 3002 - 3011.
Makoto Hashimoto, J. Biol. Chem., May 2004, 279: 23622 - 23629.
Cristine Alves da Costa, J. Biol. Chem., Sep 2003, 278: 37330 - 37335.
Heather Snyder, J. Biol. Chem., Mar 2005, 280: 7562 - 7569.Aliases: 14 kDa brain-specific protein antibody, Beta-synuclein antibody, Phosphoneuroprotein 14 antibody, PNP14 antibody, Sncb antibody, Synuclein beta antibody, SYUB_HUMAN antibody
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UniProt
- Q16143
抗原
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