SHB 抗体 (C-Term)
Quick Overview for SHB 抗体 (C-Term) (ABIN7180246)
抗原
See all SHB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 人
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from C-terminal of Human SHB.
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亚型
- IgG
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应用备注
- WB:1:500-1:3000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))
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别名
- SHB
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背景
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Background: Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.
Welsh M., Oncogene 9:19-27(1994).
Humphray S.J., Nature 429:369-374(2004).
Mural R.J., Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.Aliases: bA3J10.2 antibody, OTTHUMP00000021397 antibody, RP11 3J10.8 antibody, RP113J10.8 antibody, SH2 domain containing adapter protein B antibody, SH2 domain-containing adapter protein B antibody, SHB (Src homology 2 domain containing) adaptor protein B antibody, SHB adaptor protein (a Src homology 2 protein) antibody, SHB adaptor protein antibody, Shb antibody, SHB_HUMAN antibody, Src homology 2 domain containing adaptor protein B antibody, Src homology 2 protein antibody
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UniProt
- Q15464
抗原
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