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MBD3 抗体 (C-Term)

This anti-MBD3 antibody is a 兔 多克隆 antibody detecting MBD3 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7180199
发货至: 中国

Quick Overview for MBD3 抗体 (C-Term) (ABIN7180199)

抗原

See all MBD3 抗体
MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

适用

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宿主

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克隆类型

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多克隆

标记

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This MBD3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    C-Term

    交叉反应

    人, 小鼠

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from C-terminal of Human MBD3.

    亚型

    IgG
  • 应用备注

    WB:1:500-1:3000,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

    别名

    MBD3

    背景

    Background: Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (. Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (). Recruits histone deacetylases and DNA methyltransferases.

    Hendrich B., Mol. Cell. Biol. 18:6538-6547(1998).
    Grimwood J., Nature 428:529-535(2004).
    Tatematsu K., Genes Cells 5:677-688(2000).

    Aliases: AI181826 antibody, AU019209 antibody, MBD 3 antibody, Mbd3 antibody, MBD3: methyl CpG binding domain protein 3 antibody, MBD3_HUMAN antibody, Methyl CpG binding domain protein 3 antibody, Methyl CpG binding protein MBD3 antibody, Methyl-CpG-binding domain protein 3 antibody, Methyl-CpG-binding protein MBD3 antibody

    UniProt

    O95983

    途径

    Chromatin Binding
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