MBD3 抗体 (C-Term)
Quick Overview for MBD3 抗体 (C-Term) (ABIN7180199)
抗原
See all MBD3 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- C-Term
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                                            交叉反应
- 人, 小鼠
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                                            纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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                                            免疫原
- Synthesized peptide derived from C-terminal of Human MBD3.
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                                            亚型
- IgG
 
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                                            应用备注
- WB:1:500-1:3000,
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C,-80 °C
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                                            储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
 
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    - MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
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                                            别名
- MBD3
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                                            背景
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                        Background: Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (. Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (). Recruits histone deacetylases and DNA methyltransferases. 
 Hendrich B., Mol. Cell. Biol. 18:6538-6547(1998).
 Grimwood J., Nature 428:529-535(2004).
 Tatematsu K., Genes Cells 5:677-688(2000).Aliases: AI181826 antibody, AU019209 antibody, MBD 3 antibody, Mbd3 antibody, MBD3: methyl CpG binding domain protein 3 antibody, MBD3_HUMAN antibody, Methyl CpG binding domain protein 3 antibody, Methyl CpG binding protein MBD3 antibody, Methyl-CpG-binding domain protein 3 antibody, Methyl-CpG-binding protein MBD3 antibody 
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                                            UniProt
- O95983
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                                            途径
- Chromatin Binding
 抗原
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