GNE 抗体 (C-Term)
Quick Overview for GNE 抗体 (C-Term) (ABIN7180179)
抗原
See all GNE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 人
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from C-terminal of Human GNE.
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亚型
- IgG
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应用备注
- WB:1:500-1:3000, IHC:1:50-1:100,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GNE (Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE))
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别名
- GNE
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背景
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Background: Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Plays an essential role in early development By similarity. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells.
Lucka L., FEBS Lett. 454:341-344(1999).
Seppala R., Am. J. Hum. Genet. 64:1563-1569(1999).
Huizing M., Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.Aliases: 2310066H07Rik antibody, Bifunctional UDP N acetylglucosamine 2 epimerase/N acetylmannosamine kinase antibody, DMRV antibody, GLCNE_HUMAN antibody, Glucosamine (UDP N acetyl) 2 epimerase/N acetylmannosamine kinase antibody, GNE antibody, IBM2 antibody, ManAc kinase antibody, N acylmannosamine kinase antibody, N-acetylmannosamine kinase antibody, NM antibody, RP23-209M8.6 antibody, Uae1 antibody, UDP GlcNAc 2 epimerase antibody, UDP GlcNAc 2 epimerase/ManAc kinase antibody, UDP N acetylglucosamine 2 epimerase/N acetylmannosamine kinase antibody, UDP-GlcNAc-2-epimerase antibody, UDP-GlcNAc-2-epimerase/ManAc kinase antibody, Uridine diphosphate N acetylglucosamine 2 epimerase antibody, Uridine diphosphate-N-acetylglucosamine-2-epimerase antibody
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UniProt
- Q9Y223
抗原
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