CDCA2 抗体 (C-Term)
Quick Overview for CDCA2 抗体 (C-Term) (ABIN7180137)
抗原
See all CDCA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 人
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from C-terminal of Human CDCA2.
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亚型
- IgG
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应用备注
- WB:1:500-1:3000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CDCA2 (Cell Division Cycle Associated 2 (CDCA2))
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别名
- CDCA2
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背景
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Background: Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.
Walker M.G., Curr. Cancer Drug Targets 1:73-83(2001).
Ota T., . Genet. 36:40-45(2004).
Olsen J.V., Cell 127:635-648(2006).Aliases: CDCA2Cell division cycle-associated protein 2 antibody, Recruits PP1 onto mitotic chromatin at anaphase protein antibody, Repo-Man antibody
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UniProt
- Q69YH5
抗原
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