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MITF 抗体 (Ser73, Ser180)

This 兔 多克隆 anti-MITF antibody specifically detects MITF in WB, IHC, IF 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7180048
发货至: 中国
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Quick Overview for MITF 抗体 (Ser73, Ser180) (ABIN7180048)

抗原

See all MITF 抗体
MITF (Microphthalmia-Associated Transcription Factor (MITF))

适用

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宿主

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克隆类型

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多克隆

标记

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This MITF antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
  • 抗原表位

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    Ser73, Ser180

    原理

    MITF (Ab-180/73) Antibody

    交叉反应

    小鼠

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized non-phosphopeptide derived from Human MITF around the phosphorylation site of serine 180/73 (P-N-S(p)-P-M).

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    MITF (Microphthalmia-Associated Transcription Factor (MITF))

    别名

    MITF

    背景

    Background: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.

    J

    Aliases: BHLHE32 antibody, bHLHe32 antibody, Class E basic helix-loop-helix protein 32 antibody, CMM8 antibody, Homolog of mouse microphthalmia antibody, Mi antibody, Microphthalmia associated transcription factor antibody, Microphthalmia, mouse, homolog of antibody, Microphthalmia-associated transcription factor antibody, MITF antibody, MITF_HUMAN antibody, mitfa antibody, nacre antibody, WS2 antibody, WS2A antibody, z3A.1 antibody

    UniProt

    O75030

    途径

    Chromatin Binding
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