MITF 抗体 (Ser73, Ser180)
Quick Overview for MITF 抗体 (Ser73, Ser180) (ABIN7180048)
抗原
See all MITF 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- Ser73, Ser180
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                                            交叉反应
- 人, 小鼠
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                                            纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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                                            免疫原
- Synthesized non-phosphopeptide derived from Human MITF around the phosphorylation site of serine 180/73 (P-N-S(p)-P-M).
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                                            亚型
- IgG
 
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    - 
                                            应用备注
- WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C,-80 °C
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                                            储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
 
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    - MITF (Microphthalmia-Associated Transcription Factor (MITF))
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                                            别名
- MITF
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                                            背景
- 
                        Background: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium. 
 JAliases: BHLHE32 antibody, bHLHe32 antibody, Class E basic helix-loop-helix protein 32 antibody, CMM8 antibody, Homolog of mouse microphthalmia antibody, Mi antibody, Microphthalmia associated transcription factor antibody, Microphthalmia, mouse, homolog of antibody, Microphthalmia-associated transcription factor antibody, MITF antibody, MITF_HUMAN antibody, mitfa antibody, nacre antibody, WS2 antibody, WS2A antibody, z3A.1 antibody 
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                                            UniProt
- O75030
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                                            途径
- Chromatin Binding
 抗原
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