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CBX5 抗体 (Ser92)

This anti-CBX5 antibody is a 兔 多克隆 antibody detecting CBX5 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7180021
发货至: 中国

Quick Overview for CBX5 抗体 (Ser92) (ABIN7180021)

抗原

See all CBX5 抗体
CBX5 (Chromobox Homolog 5 (CBX5))

适用

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宿主

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克隆类型

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  • 1
多克隆

标记

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This CBX5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    Ser92

    交叉反应

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized non-phosphopeptide derived from Human HP1 alpha around the phosphorylation site of serine 92 (R-K-S(p)-N-F).

    亚型

    IgG
  • 应用备注

    WB:1:500-1:3000, IHC:1:50-1:100,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    CBX5 (Chromobox Homolog 5 (CBX5))

    别名

    CBX5

    背景

    Background: Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

    Saunders W.S., J. Cell Sci. 104:573-582(1993).
    The MGC Project Team, Genome Res. 14:2121-2127(2004).
    Ye Q., J. Biol. Chem. 271:14653-14656(1996).

    Aliases: Antigen p25 antibody, CBX5 antibody, CBX5_HUMAN antibody, CG8409 antibody, Chromobox 5 antibody, Chromobox homolog 5 (HP1 alpha homolog, Drosophila) antibody, Chromobox homolog 5 antibody, Chromobox protein homolog 5 antibody, Epididymis luminal protein 25 antibody, HEL25 antibody, Heterochromatin protein 1 alpha antibody, Heterochromatin protein 1 antibody, Heterochromatin protein 1 homolog alpha antibody, HP1 alpha antibody, HP1 alpha homolog antibody, HP1 antibody, HP1A antibody, HP1Hs alpha antibody, Su(var)205 antibody

    UniProt

    P45973
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