Cyclin C 抗体 (Ser275)
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北京 101111
Quick Overview for Cyclin C 抗体 (Ser275) (ABIN7179998)
抗原
See all Cyclin C (CCNC) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Ser275
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原理
- CCNC (Ab-275) Antibody
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交叉反应
- 小鼠
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized non-phosphopeptide derived from Human Cyclin C around the phosphorylation site of serine 275 (N-G-S(p)-Q-N).
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亚型
- IgG
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anti-Cyclin C (CCNC) (AA 1-283) antibody
CCNC 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin C (CCNC) (AA 240-283) antibodyCCNC 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin C (CCNC) (AA 23-100) antibodyCCNC 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin C (CCNC) (C-Term) antibodyCCNC 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin C (CCNC) antibodyCCNC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin C (CCNC) (AA 1-30) antibodyCCNC 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Cyclin C (CCNC) (AA 1-30), (N-Term) antibodyCCNC 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB14994 unconjugated
anti-Cyclin C (CCNC) (AA 234-283), (pSer275) antibodyCCNC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin C (CCNC) (AA 221-249) antibodyCCNC 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin C (CCNC) (AA 1-30), (N-Term) antibodyCCNC 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Cyclin C (CCNC)
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别名
- CCNC
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背景
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Background: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.
Lew D.J., Cell 66:1197-1206(1991).
Li H., Genomics 32:253-259(1996).
Mungall A.J., Nature 425:805-811(2003).Aliases: ccnc antibody, CCNC_HUMAN antibody, CycC antibody, Cyclin C antibody, Cyclin-C antibody, hSRB11 antibody, OTTHUMP00000016897 antibody, SRB11 homolog antibody
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UniProt
- P24863
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途径
- Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha
抗原
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