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CNOT2 抗体 (Ser101)

The 兔 多克隆 anti-CNOT2 antibody (ABIN7179994) specifically detects CNOT2 in ELISA 和 WB. The antibody is reactive with 人 samples.
产品编号 ABIN7179994
发货至: 中国
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Quick Overview for CNOT2 抗体 (Ser101) (ABIN7179994)

抗原

See all CNOT2 抗体
CNOT2 (CCR4-NOT Transcription Complex, Subunit 2 (CNOT2))

适用

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宿主

  • 59
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克隆类型

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多克隆

标记

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This CNOT2 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB)
  • 抗原表位

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    Ser101

    原理

    CNOT2 (Ab-101) Antibody

    交叉反应

    小鼠

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized non-phosphopeptide derived from Human CNOT2 around the phosphorylation site of serine 101 (S-L-S(p)-Q-G).

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    CNOT2 (CCR4-NOT Transcription Complex, Subunit 2 (CNOT2))

    别名

    CNOT2

    背景

    Background: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation, the repressive function may specificly involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of emryonic stem (ES) cell identity.

    Albert T.K., Nucleic Acids Res. 28:809-817(2000).
    Zhang Q.-H., Genome Res. 10:1546-1560(2000).
    Ota T., Nat. Genet. 36:40-45(2004).

    Aliases: CCR4 associated factor 2 antibody, CCR4 NOT transcription complex subunit 2 antibody, CCR4-associated factor 2 antibody, CCR4-NOT transcription complex subunit 2 antibody, CDC36 antibody, CNOT2 antibody, CNOT2_HUMAN antibody, HSPC131 antibody, MSTP046 antibody, Negative regulator of transcription 2 antibody, NOT2 (negative regulator of transcription 2 yeast) homolog antibody, NOT2 antibody, NOT2H antibody

    UniProt

    Q9NZN8

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance
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