RUNX1 抗体 (Ser435)
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北京 101111
Quick Overview for RUNX1 抗体 (Ser435) (ABIN7179972)
抗原
See all RUNX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Ser435
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原理
- RUNX1 (Ab-435) Antibody
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交叉反应
- 小鼠
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized non-phosphopeptide derived from Human AML1 around the phosphorylation site of serine 435 (S-N-S(p)-P-T).
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亚型
- IgG
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anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 150-250) antibody
RUNX1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 210-310) antibodyRUNX1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2C10 unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (pSer304) antibodyRUNX1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) antibodyRUNX1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 210-310) antibodyRUNX1 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 3A1 unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 227-255) antibodyRUNX1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) antibodyRUNX1 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 5A1 unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 237-337) antibodyRUNX1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6C12A5 unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 200-233), (Middle Region) antibodyRUNX1 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 227-255) antibodyRUNX1 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB15210 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
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别名
- RUNX1
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背景
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Background: CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits KAT6B-dependent transcriptional activation.
Miyoshi H., Proc. Natl. Acad. Sci. U.S.A. 88:10431-10434(1991).
Sacchi N., Genes Chromosomes Cancer 11:226-236(1994).
Nucifora G., Blood 81:2728-2734(1993).Aliases: Acute myeloid leukemia 1 antibody, Acute myeloid leukemia 1 protein antibody, alpha subunit core binding factor antibody, AML 1 antibody, AML1 antibody, AML1 EVI 1 antibody, AML1 EVI 1 fusion protein antibody, Aml1 oncogene antibody, AMLCR 1 antibody, AMLCR1 antibody, CBF alpha 2 antibody, CBF-alpha-2 antibody, CBFA 2 antibody, CBFA2 antibody, Core binding factor alpha 2 subunit antibody, Core binding factor runt domain alpha subunit 2 antibody, Core-binding factor subunit alpha-2 antibody, EVI 1 antibody, EVI1 antibody, HGNC antibody, Oncogene AML 1 antibody, Oncogene AML-1 antibody, OTTHUMP00000108696 antibody, OTTHUMP00000108697 antibody, OTTHUMP00000108699 antibody, OTTHUMP00000108700 antibody, OTTHUMP00000108702 antibody, PEA2 alpha B antibody, PEA2-alpha B antibody, PEBP2 alpha B antibody, PEBP2-alpha B antibody, PEBP2A2 antibody, PEBP2aB antibody, Polyomavirus enhancer binding protein 2 alpha B subunit antibody, Polyomavirus enhancer-binding protein 2 alpha B subunit antibody, Run1 antibody, Runt related transcription factor 1 antibody, Runt-related transcription factor 1 antibody, RUNX 1 antibody, Runx1 antibody, RUNX1_HUMAN antibody, SL3 3 enhancer factor 1 alpha B subunit antibody, SL3-3 enhancer factor 1 alpha B subunit antibody, SL3/AKV core binding factor alpha B subunit antibody, SL3/AKV core-binding factor alpha B subunit antibody
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UniProt
- Q01196
抗原
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