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MBNL3 抗体 (AA 251-354)

This anti-MBNL3 antibody is a 兔 多克隆 antibody detecting MBNL3 in ELISA, WB, IF (cc), IF (p), IHC (fro) 和 IHC (p). Suitable for 小鼠.
产品编号 ABIN713756
发货至: 中国

Quick Overview for MBNL3 抗体 (AA 251-354) (ABIN713756)

抗原

See all MBNL3 抗体
MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))

适用

  • 26
  • 1
小鼠

宿主

  • 24
  • 2

克隆类型

  • 25
  • 1
多克隆

标记

  • 12
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MBNL3 antibody is un-conjugated

应用范围

  • 14
  • 12
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-354

    交叉反应

    小鼠

    预测反应

    Human,Rat,Cow,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human MBNL3

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))

    别名

    MBNL3

    背景

    Synonyms: MBLX, CHCR, Cys3His CCG1 required protein, MBLX39, MBNL 3, MBXL, Muscleblind like protein 3, Muscleblind like X linked protein, Protein HCHCR, MBNL3_HUMAN.

    Background: MBNL3 has been shown to inhibit muscle differentiation. MBNL3 belongs to a highly conserved family of tissue-specific alternative splicing regulators. This family is known to regulate terminal muscle differentiation through alternative splicing control and several groups have suggested that the family participates in the differentiation of photoreceptors, neurons, adipocytes and blood cell types. MBNL3 is expressed in myoblasts, muscle precursor cells, and during the early stages of myogenesis, but is detected at very low levels in terminally differentiated myotubes. MBNL proteins have been shown to sequester foci of expanded-repeat transcripts and are thought to therefore play a role in the molecular pathology of a group of neuromuscular diseases including the Myotonic Dystrophies.

    基因ID

    55796

    UniProt

    Q9NUK0

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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