Streptococcal Pyrogenic Exotoxin B (SPEB) (AA 146-398) 抗体
Quick Overview for Streptococcal Pyrogenic Exotoxin B (SPEB) (AA 146-398) 抗体 (ABIN7179505)
抗原
See all Streptococcal Pyrogenic Exotoxin B (SPEB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 146-398
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交叉反应
- Streptococcus pyogenes
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Streptococcus pyogenes serotype M28 Streptopain protein (146-398AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:5000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Streptococcal Pyrogenic Exotoxin B (SPEB)
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别名
- speB
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背景
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Background: Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing (By similarity).
Aliases: speB antibody, M28_Spy1721 antibody, Streptopain antibody, EC 3.4.22.10 antibody, Exotoxin type B antibody, SPE B antibody, Streptococcal cysteine proteinase antibody, Streptococcus peptidase A antibody, SPP antibody
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UniProt
- Q48R29
抗原
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